बेटडेक्स सल्फोबुटिल ईथर सोडियम के लिए एक और नाम सल्फोब्यूटाइल ईथर बीटा साइक्लोडेक्सट्रिन सोडियम है जो एक नया प्रकार का अत्यधिक भंग साइक्लोडेक्सट्रिन है, और डेली चीन में एक पेशेवर साइक्लोडेक्सट्रिन निर्माता है। सल्फोबुटिल ईथर बीटा साइक्लोडेक्सट्रिन सोडियम कैस 182410-00-0
Sulfobutyl Ether Beta Cyclodextrin Sodium Cas 182410-00-0 is a new type of anionic high soluble cyclodextrin derivatives in China DELI, which can be used as a solubilizer, wetting agent, chelating agent (complexing agent) and polyvatent masking agent.
Sulfobutyl Ether Beta Cyclodextrin Sodium Cas 182410-00-0 has been used in injection, oral, nasal and eye medicines. It has a special affinity and inclusion for nitrogen drugs. Increase the drug's stability ,solubility ,safety (Include drug molecules to form non-covalent). Reduce renal toxicity, ease drug hemolysis. Sulfobutyl Ether Beta Cyclodextrin Sodium also can control the drug release rate, cover the bad smell.
Sulfobutyl Ether Beta Cyclodextrin Sodium Cas 182410-00-0
[CAS NO]: 128410-00-0
[Molecular formula]: C42H70-nO35·(C4H8SO3Na)n
[Grade]: Injection grade
[Executive standard]: USP/EP/Enterprise standard
[Specification]: 500g/Bag; 1kg/Bag; 10kg/bag; 10kg/drum.
[Application Area]: Medicine
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Description and Solubility/ see details in the USP Monograph |
White to off-white,amorphous powder.Freely soluble in water;sparingly soluble in methanol;practically insoluble in ethanol,in n-hexane,in 1-butanol,in acetonitrile,in 2-propanol,and in ethylacetate |
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Identification A/IR; USP<197K> |
Complies with SBECD reference |
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Identification B/(Assay method)HPLC; USP<621> |
tR of the major peak complies with SBECD reference |
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Identification C/CE; USP<1053> |
It meets the requirements of the test for Average Degree of Substitution. |
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Identification D/USP<191> |
Positive test for sodium |
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Assay/HPLC;USP<621> |
95.0%-105.0% on the anhydrous basis |
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Limit of Beta Cyclodextrin(Betadex)/IC; USP<621>;USP<1065> |
NMT 0.1% |
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Limit of 1,4-Butane Sultone /GC;USP<621>, |
NMT 0.5ppm |
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Limit of Sodium chloride /IC; USP<621>;USP<1065> |
NMT 0.2% |
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Limit of 4-Hydroxybutane-1-sulfonic acid /IC;USP<621>;USP<1065> |
NMT 0.09% |
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Limit of Bis(4-sulfobutyl) ether disodium /IC;USP<621>;USP<1065> |
NMT 0.05% |
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Bacterial Endotoxins Test/USP<85> |
≤10EU/g |
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Microbial Enumeration Tests/USP<61> |
TAMC≤100cfu/g TYMC≤50 cfu/g |
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Tests for Specified Microorganisms/USP<62> |
Absence of Escherichia Coli/1g |
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Clarity of Solution(30%,w/v)/visual;see details in the USP Monograph |
The solution is clear, and essentially free from particles of foreign matter. |
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Average Degree of Substitution [DS]/CE;USP<1053> |
6.2-6.9 |
